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52 courses found.
BIOLOGY AND BIOMEDICAL SCIENCES (L41)  (Dept. Info)Arts & Sciences  (Policies)SP2023

L41 BIOL 1440Ampersand: The Biology of Cancer Part II4.0 Units
Description:Cancer is poised to overtake heart disease as the number one cause of death in the United States and represents a significant burden to the U.S. health system. As such, a deeper understanding of the underlying biology of human cancers and their treatment modalities will be important for those pursuing a future in the health sciences. In this interactive 2nd-semester course, we continue our exploration of the "hallmarks of cancer," emphasizing the dysfunction of essential biological processes like cell proliferation, programmed cell death, energy metabolism, and immune surveillance. Classical diagnosis and treatment methods are compared with newer strategies, such as targeted and immune therapies. Finally, the growing role of personalized medicine and "omics" technologies in tumor classification, patient prognosis, and therapy are discussed. The course is a mix of lectures, student-led discussions/presentations, and activities. Lectures provide an overview of each topic, while activities and discussions of cutting-edge oncology topics in the news and primary literature familiarize students with current trends in cancer research/treatment as well as enhance reading and critical analysis skills. Students choose a specific type of cancer for further study and near the end of the semester prepare a presentation to the class on its molecular and cellular etiology, epidemiology, pathology, diagnosis, and current/future treatment options. Midterm Exams, which attendance is required, will be administered on Wednesday, March 1, 6:30 - 8:30 pm & Wednesday, April 12, 6:30 - 8:30 pm. Prerequisite: Completion of "The Biology of Cancer, Part I" (BIOL 144); enrollment is limited to students in the "Hallmarks of Cancer & Patient Care" program. Grade Options: Credit, Pass/Fail
Attributes:A&SFYSA&S IQNSM
Instruction Type:Classroom instruction Grade Options:CP Fees:
Course Type:HomeSame As:N/AFrequency:Every 2 Years / History
SecDays       TimeBuilding / RoomInstructorFinal ExamSeatsEnrollWaits
01M--R---2:30P-4:30PSimon / 017 SmithMay 8 2023 3:30PM - 5:30PM0200
Syllabi are provided to students to support their course planning; refer to the syllabus for constraints on use.
Waits Not Allowed

L41 BIOL 1772Special Topics in Biology: Plant-Microbe Interactions1.0 Unit
Description:This is a research-based laboratory course offered by Dr. Barbara Kunkel in the Biology Department. The small class size and laboratory setting of the course is intended to foster development of student-professor mentoring relationships. Time commitment (weekly): 2 hours in lab, 1 hour of discussion (1 unit, P/F). Class size: 4 students Prerequisite: Permission of Instructor Research Question. Microbial organisms play very important roles in the lives of plants and animals. For example, in nature as well as in agricultural settings, the communities of microorganisms that grow near or on plants influence the growth and overall health of these plants. These plant-associated microbial communities are highly complex, and are comprised of thousands of different species, including bacteria and fungi. However, neither the role of individual microbial species within the larger microbial community, nor how such a community is beneficial to plants, is well understood. Each year the students in Bio1771 explore a different topic related to interactions between plants and their associated microbes. During the 2020/2021 academic year our research will focus on virulence mechanisms used by the plant pathogen Pseudomonas syringae to promote disease in plants. Recent research in the Kunkel lab has revealed that the plant hormone auxin promotes disease development in interactions between P. syringae strain PtoDC3000 and one of its host, Arabidopsis thaliana, a weedy plant in the mustard family. Auxin acts through at least two different mechanisms to promote disease, including 1) suppressing defense responses in the plant and 2) regulating gene expression in the pathogen. We will investigate this second activity by screening for and characterizing PtoDC3000 mutants that do not properly respond to auxin. Students will spend two hours per week in lab carrying out bacteriological and molecular biology experiments. Over the course of the semester, students will be exposed to a variety of fundamental topics in biology, including: bacteriology, plant growth and development, pathogenic plant-microbe interactions, and key concepts in genetics, molecular biology and biochemistry. The students will also meet with Dr. Kunkel for one hour per week to discuss a variety of topics chosen to explore: i) basic concepts in chemistry, biochemistry and molecular biology, ii) learning and study strategies, and iii) other topics related to thriving at WUSTL. This is a cotinumation of Bio1771, 0nly students enrolled in Bio1771 during Fall are permitted to enroll in this course.
Instruction Type:Independent study, tutorial, or other Grade Options:P Fees:
Course Type:HomeSame As:N/AFrequency:Annually / History

L41 BIOL 200Introduction to ResearchVar. Units (max = 3.0)
SecDays       TimeBuilding / RoomInstructorFinal ExamSeatsEnrollWaits
01TBASee Dept / [TBA], AkkNo Final000
02TBASee Dept / Al-HasaniNo Final000
03TBASee Dept / BaldridgeNo Final000
04TBASee Dept / BoseNo Final000
05TBASee Dept / BrookheartNo Final000
06TBASee Dept / BudgeNo Final000
07TBASee Dept / ChaudhuriNo Final000
08TBASee Dept / CorboNo Final000
09TBASee Dept / Dantas, ClarkNo Final000
10TBASee Dept / DingNo Final000
11TBATBADingNo Final000
12TBASee Dept / HirbeNo Final000
13TBASee Dept / JezNo Final000
14TBASee Dept / FinckNo Final000
15TBASee Dept / KranzNo Final000
16TBASee Dept / KulkarniNo Final000
17TBASee Dept / LakeNo Final000
18TBASee Dept / LiNo Final000
19TBASee Dept / LimbrickNo Final000
20TBASee Dept / LopezNo Final000
21TBATBAMcCallNo Final000
22TBATBAPerlmanNo Final000
23TBATBARazaniNo Final000
24TBATBARemediNo Final000
25TBATBASchellerNo Final000
26TBATBASchillingNo Final000
27TBATBAStallingsNo Final000
28TBATBAWeberNo Final000
29TBATBABerezinNo Final000
30TBATBABoltonNo Final000
31TBATBADingNo Final000
32TBATBADipersioNo Final000
33TBATBAFrolovaNo Final000
34TBATBAGordonNo Final000
35TBATBALaidlawNo Final000
36TBATBALodhiNo Final000
37TBATBALososNo Final000
38TBATBARentschlerNo Final000
39TBATBAStoneNo Final000
40TBATBAVierstraNo Final000
41TBATBAAmarasingheNo Final000
42TBATBABednarskiNo Final000
43TBATBA[TBA]No Final000
44TBATBARutherfordNo Final000
45TBATBAAzabNo Final000
46TBATBALiNo Final000
47TBATBABarnesNo Final000
48TBATBABen-ShaharNo Final000
49TBATBAFleckensteinNo Final000
50TBATBAKrollNo Final000
51TBATBAPignatelliNo Final000
52TBATBAOlsenNo Final000
53TBATBA[TBA]No Final000
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57TBATBA[TBA]No Final000
58TBATBA[TBA]No Final000
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60TBATBA[TBA]No Final000
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62TBATBA[TBA]No Final000
63TBATBA[TBA]No Final000